With degrees in genetics and medicine and her years of professional research in minimally invasive aesthetic medicine, Dr. Gail Humble isn’t one to be duped by product marketing campaigns. And in an industry overflowing with miracle creams and buzzwords, Humble found herself questioning why so many beauty products aggressively marketed to female consumers lack scientific proof of efficacy – over-promising on the package, yet under-delivering on the skin.
A geneticist by training, Humble spent years pioneering minimally invasive and injection based aesthetic medical procedures. More interested in the science that drives transformative skincare products than in unsubstantiated hype, Dr. Humble was inspired to solve the problem she was observing, and saw an opportunity to build skincare that actually interacts with the biology of aging.
“As women, many of us live under relentless pressure to look our best, yet flawless skin is hardly universal,” she says. “We also represent a powerful share of the beauty market, and too often we’re sold costly potions heavy on promises and light on proof — treated as a “target audience”, rather than as discerning individuals.” Dr. Humble set out to change that.
“With rapid advances in genetics and regenerative medicine, we can now craft skincare that engages the biology of aging itself—protective, regenerative, and preventive—so results are grounded in science rather than hype,” she said.
As the founder and CEO of a biotech company, she’s not chasing the next trend in beauty, she’s rewriting the biology of aging itself. Bringing the Klotho Gene into Skincare: But What is It?Invested in using her knowledge of regenerative medicine to reverse the signs of aging, Humble did a deep dive into genetic research, and came upon a game changer: the Klotho gene.
Already well recognized for her work in aesthetic medical practices, Humble has since become one of the world’s leading experts on the Klotho gene, which she calls “a master regulator of aging, with youth-preserving effects.”
Realizing the gene’s potential, Humble developed the first biotech skincare brand to harness the Klotho protein – the body’s natural age-suppressor – in combination with second-generation growth factors.
On Using Her Seat at the Table
Once Dr. Humble reached her goal of patenting Klotho Skin’s formulations and launching a revolutionary skincare line, the newly minted entrepreneur reflected on how she could be a leader in the science field, and prioritize lifting up other women.
Humble’s career has long blurred the boundaries between medicine, science, and entrepreneurship. Before launching Klotho Skin, she was a pioneer in minimally invasive aesthetic medicine and founded the Aesthetic Anti-Ageing Institute in San Francisco and Los Angeles.
Recognition as a thought leader has been exhilarating, she says, but not without its reminders of how male-dominated the scientific and medical communities can feel.
She draws strength from a famous line by Madeleine Albright: “There’s a special place in hell for women who don’t help other women.”
“Those words guide me,” Humble reflects.
“Women are still expected to work harder, look younger, and shoulder scrutiny that men rarely face,” she says. “Recognition gives me a platform to share what I’ve learned, open doors, and help other women build their own brands. It’s both a privilege and a responsibility, and one I don’t take lightly.”
Beauty with a Conscience
Gail Humble’s scientific innovations are already trailblazers in the lab. But the way she leads her company is also socially conscious in its mission to create products from clean, sustainably sourced ingredients, and pledge its future profits to Women for Women International, a nonprofit that supports women in war-torn communities.
“This is deeply personal to me,” Humble says.
“In conflicts around the world, women too often pay the highest price: targeted with gender-based violence, displaced, and left to rebuild with limited support,” she says. “That’s why we’ve pledged to direct a portion of our future profits to Women for Women International. Although we’re not yet profitable, our commitment is firm: as we grow, so will our giving. For us, beauty is inseparable from humanity.”
When Dr. Gail Humble speaks of the legacy she would wish to leave to female entrepreneurs, it is as much about people as it is about products. There can be no doubt that she is pushing science forward. But she is also modeling a new brand of leadership that fits her personal values: one that insists on integrity, inclusion and impact.
“Skincare should be about more than appearances,” she says.
“It should be about empowerment—scientifically, socially, and personally.”
Under Humble’s leadership, Klotho Skin is proving that beauty and biotechnology can share the same DNA, and that women belong at the helm of the biotech industry.
Dr. Gail Humble is the Founder and CEO of Klotho Skin—the first biotech skincare brand to harness the Klotho gene, often called the body’s natural “age-suppressor.” Beyond her scientific innovation, Gail’s story is one of female leadership in a male-dominated field, pioneering aesthetic medicine, and building a socially conscious brand that commits future profits to support women in conflict zones. Dr. Humble is a fellow of the Aesthetic Anti Aging Congress, and she is boarded by the American Board of Laser Medicine and Surgery. She is the author of multiple medical and non-medical articles as well as several medical journals, including Dermatologic Surgery and the Journal of Facial and Plastic Surgery. Dr. Humble served as principle investigator of multiple studies on Sculptra and its use in revolumization. She believes that beauty is a reflection of the person inside. When we feel young and beautiful, or handsome, our image in the mirror should reflect that. Follow Dr. Gail Humble on Instagram and Facebook, as well as Klotho Skin on Instagram and Facebook.
